Insulin – a series part I

Part I – (Making The Molecules)

We know we need it. We know we don’t want to be resistant to it …

Does anyone know what insulin really is?

Let’s start with cells – there are little bits and pieces inside our cells called organelles.

A very important yet INACTIVE molecule called proinsulin is produced on the Rough Endoplasmic Reticulum (an organelle)

The Golgi complex / Golgi apparatus (yet another organelle) Cleves this large inactive molecule (proinsulin) to produce a smaller active molecule called insulin. Tada! Insulin! This last part takes place inside the Golgi complex of the beta cells in the pancreas.

This means that insulin starts as a larger inactive molecule, and that the Golgi complex in the beta cells of the pancreas convert this molecule into it’s active form.


What could this possibly mean?

Here’s an interesting article highlighting how this info has REAL WORLD implications… . And now you know what on earth they mean by Endoplasmic Reticulum in this article!

Endoplasmic Reticulum Stress and Insulin Biosynthesis: A Review

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