Insulin – a series part I

Part I – (Making The Molecules)

We know we need it. We know we don’t want to be resistant to it …

Does anyone know what insulin really is?

Let’s start with cells – there are little bits and pieces inside our cells called organelles.

A very important yet INACTIVE molecule called proinsulin is produced on the Rough Endoplasmic Reticulum (an organelle)

The Golgi complex / Golgi apparatus (yet another organelle) Cleves this large inactive molecule (proinsulin) to produce a smaller active molecule called insulin. Tada! Insulin! This last part takes place inside the Golgi complex of the beta cells in the pancreas.

This means that insulin starts as a larger inactive molecule, and that the Golgi complex in the beta cells of the pancreas convert this molecule into it’s active form.

#OurBodiesAreAmazing

What could this possibly mean?

Here’s an interesting article highlighting how this info has REAL WORLD implications… . And now you know what on earth they mean by Endoplasmic Reticulum in this article!

Endoplasmic Reticulum Stress and Insulin Biosynthesis: A Review

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